The American Fibromyalgia Syndrome Association, Inc.

About AFSA
What is Fibromyalgia
Projects Funded
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AFSA is an all volunteer nonprofit organization dedicated to funding research that investigates the causes and treatments for fibromyalgia syndrome.

A 501(c)3 Nonprofit Charitable Organization.

About AFSA

Our primary mission is to fund superior quality research on
fibromyalgia syndrome (FMS). Studies show that this extremely painful,
fatiguing, and often debilitating medical condition affects 3 to 5 percent
of the population.

By stepping up research on the causes and treatments for
fibromyalgia, AFSA and its generous contributors are working together
to make a difference in the lives of millions.

AFSA was formed as a 501(c)3 charity in 1994, at a time when the NIH
was spending less than a penny a patient on fibromyalgia research.
While the U.S. government’s track record on fibro has improved, AFSA
remains the only nonprofit dedicated to funding fibromyalgia research.

Our research grants (typically $50,000 to $85,000) enable scientists to
collect the vital data needed to receive large awards from the NIH or
other agencies. In addition, most AFSA awards have generated at
least one research paper in a peer-reviewed medical journal. So
funding from AFSA accomplishes two goals: (1) expands research in
targeted areas important for helping patients and (2) educating other
scientists and treating physicians about fibromyalgia.

Close to 90% of contributions to AFSA go directly to research. AFSA is
administered and run by volunteers, eliminating overhead and other
large, office expenses. The scientists who review research grant
proposals also assist AFSA on a volunteer basis.
Research Goals

Testing therapies that may greatly benefit people with fibromyalgia is a
top priority for AFSA. In fact, we funded the ground-breaking treatment
trial of low-dose naltrexone, which was shown to be more effective for
fibromyalgia than any of the FDA-approved drugs for the condition.
However, the long-term goal of better treatments will strongly rely upon
an improved understanding of what is occurring on a biochemical

With AFSA’s financial assistance, we are hopeful that the following questions can be answered about fibromyalgia:
  • What are the mechanisms involved in producing the body-wide pain?
  • Why do patients wake up from a night’s sleep feeling stiff, achy, and tired? What is happening in the brain at night to make sleep so unrefreshing?
  • How is the extreme fatigue and brain fog (jumbled thoughts and
    memory impairments) related to the abnormal physiology of
  • To what degree does treatment of muscular knots lead to reduced
    overall pain and improved function? What is the most effective
    therapy for targeting the muscle pain in fibromyalgia patients?
  • Are there medications used for other conditions that should be
    evaluated for treating people with fibromyalgia?
  • Can laboratory tests be used to accurately identify or diagnose
    patients? Also, can this information be used to determine
    disease severity or aid in predicting more successful treatments
    for individual patients?

Providing answers to the above questions will favorably impact fibromyalgia patients, which is why they form the basis of AFSA’s research-funding goals.

Why Donate to AFSA?

There are no effective therapies for the unrelenting symptoms of
fibromyalgia. This condition is often devastating to both patients and
their families. Getting talented investigators to enter the field of
fibromyalgia is essential for accelerating research and improving
treatment options. AFSA’s small grants program offers an opportunity
to these dedicated scientists to initiate new studies in fibromyalgia.

When AFSA-funded investigators are asked, "What did the AFSA
award mean to you?"—many say it was the initial stepping stone that
got them started in fibromyalgia research. Most were well-known for
their work on other painful conditions, but it was funding from AFSA
that lured these talented scientists into the field of fibromyalgia.

More effective treatments are key to making fibromyalgia manageable.
The fibromyalgia patient community has been extraordinarily generous
throughout the years, yet more donors are needed to accelerate
advances in the field. Help improve the quality of life for millions and be
a part of the solution. Make a tax-deducible donation to AFSA today.

Concerned About Donor Privacy?
For Over 25 Years, AFSA Has NEVER ...
  • Shared donor information (email, phone, address) with anyone.
  • Partnered with others, including pharmaceutical or health product companies that often view you as a marketing commodity.
  • Accepted advertising money for any reason (ads just mislead people on therapies that don’t work).
  • Been in anyone’s back pocket, behind the scenes or in front of them.
  • Taken fibromyalgia patients and our generous donors for granted.

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The American Fibromyalgia Syndrome Association, Inc. (AFSA)
PO Box 32698, Tucson, AZ 85751 • Phone: (520) 733-1570 • Fax: (520) 290-5550
Federal Tax I.D. 77-0355224 • Copyright © 1998-2021

This site is provided for informational purposes only.
Patients should always consult their physician for medical advice and treatment.